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KMID : 1123920060200040992
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Korean Journal of Oriental Physiology and Pathology
2006 Volume.20 No. 4 p.992 ~ p.996
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Effect of ’Sexiang Shuhuo Jing’ for CPK, LDH Activities and Skeletal Muscle mRNA Expression after Skeletal Muscle in Rats
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Kim Jin-Hang
Song Je-Ho
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Abstract
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The study examined clinical effect of the ’Sexiang Shuhuo Jing’ on serum CK and LDH activities and skeletal muscle mRNA expression concentration 140days after skeletal muscle injury in rats. The clinical research consisted of observing and measuring the serum CK, LDH activities and skeletal muscle mRNA expression, at the time of injury and during recovery. All experimental data were analyzed by repeated measurement with ANOVA on of SPSS(11.5v), accepting level for all significances was above The results were as follows: That skeletal muscle injury in rats there existed a substantial increase serum CK, LDH activities and expression of skeletal muscle mRNA And Sexiang Shuhuo Jing treatment group’s serum CK, LDH activities lower and faster recovery than control group. The 1 st day after skeletal muscle injury, Sexiang Shuhuo Jing treatment group’s skeletal muscle mRNA expression was much more higher than control group, after 2 day’s faster recovery normal level than control group. There existed a substantial increase again serum CK, LDH activities and skeletal muscle mRNA expression 3rd days after injury in control group. But in Sexiang Shuhuo Jing treatment group’s can’t be found that.
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KEYWORD
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Sexiang Shuhuo Jing treatment, serum CK, LDH activities, skeletal muscle injury, skeletal muscle mRNA
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